Whether you are hiding valuables or a pistol for defensive measures the QuickSafe Vent Safe ($219) is a pretty clever hiding place. I seriously doubt the typical crack-head burglar would have a chance at finding this stash.
The Vent Safe fits between your standard 16-inch studs and uses an RFID card to unlock the contents. Video of the QuickSafe Air Vent RFID Safe after the break.